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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
8.79
Human Site:
Y646
Identified Species:
14.87
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
Y646
N
E
K
A
R
L
S
Y
S
D
K
N
L
I
D
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
F677
N
E
K
P
R
L
S
F
A
D
R
A
L
I
N
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y1110
N
E
K
A
R
L
S
Y
S
D
K
N
L
I
D
Dog
Lupus familis
XP_849292
706
81555
F677
N
E
K
P
R
L
S
F
A
D
R
A
L
I
N
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
F644
N
E
K
P
Q
L
S
F
S
D
K
N
L
I
D
Rat
Rattus norvegicus
P09215
673
77502
F644
N
E
K
P
Q
L
S
F
S
D
K
N
L
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
F679
N
E
K
P
R
L
S
F
A
D
R
A
L
I
N
Chicken
Gallus gallus
NP_001006133
699
80179
Y669
N
E
K
P
K
L
S
Y
S
D
K
N
L
I
D
Frog
Xenopus laevis
NP_001084460
683
78181
F653
S
E
K
P
R
L
S
F
S
D
K
N
L
I
D
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
P557
N
E
P
I
Q
L
T
P
D
D
D
D
A
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
P644
R
E
R
V
R
L
T
P
I
D
K
E
I
L
A
Honey Bee
Apis mellifera
XP_394743
624
71014
P598
A
E
R
P
R
L
S
P
V
P
E
Q
I
L
A
Nematode Worm
Caenorhab. elegans
P34722
704
80280
P677
N
E
K
A
A
L
T
P
V
H
D
K
N
L
L
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
P558
M
E
K
V
A
L
S
P
T
D
T
S
M
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
60
100
60
N.A.
80
80
N.A.
60
86.6
80
26.6
N.A.
33.3
26.6
33.3
33.3
P-Site Similarity:
100
86.6
100
86.6
N.A.
93.3
93.3
N.A.
86.6
93.3
93.3
53.3
N.A.
60
53.3
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
22
15
0
0
0
22
0
0
22
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
86
15
8
0
0
43
% D
% Glu:
0
100
0
0
0
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
15
65
0
% I
% Lys:
0
0
79
0
8
0
0
0
0
0
50
8
0
0
8
% K
% Leu:
0
0
0
0
0
100
0
0
0
0
0
0
65
29
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
72
0
0
0
0
0
0
0
0
0
0
43
8
0
22
% N
% Pro:
0
0
8
58
0
0
0
36
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
22
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
15
0
58
0
0
0
0
0
22
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
79
0
43
0
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
22
0
8
0
8
0
0
0
0
% T
% Val:
0
0
0
15
0
0
0
0
15
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _